3-Dimensional Imaging At Nanometer Resolutions

An apparatus and method for enabling precise, 3-dimensional, photoactivation localization microscopy (PALM).

Available for  

  • thumbnail of
  • Feynman Center
  • (505) 665-9090
  • Email

3-Dimensional Imaging At Nanometer Resolutions

An apparatus and method for enabling precise, 3-dimensional, photoactivation localization microscopy (PALM) using selective, two-photon activation of fluorophores in a single z-slice of a sample in cooperation with time-gated imaging for reducing the background radiation from other image planes to levels suitable for single-molecule detection and spatial location, are described.

U.S. Patent No.: 7,675,045 (DOE S-112,966)

Patent Application Filing Date: October 9, 2008

Patent Issue Date: March 9, 2010

Licensing Status:

Available for Express Licensing(?). View terms and a sample license agreement.

For more information, contact licensing@lanl.gov.

You can also view this technology on flintbox.

Visit Blogger Join Us on Facebook Follow Us on Twitter See our Flickr Photos Watch Our YouTube Videos Find Us on LinkedIn Find Us on iTunes