Group Contacts
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B-7 Strives to Understand Emerging and Engineered Health ThreatsThis group specializes in studying methods to protect humans and other organisms from pathogens and disease – both naturally occurring ones and those that could be used as biothreat agents. Research areas include host-pathogen biology, microbial pathogenesis, molecular signaling, structural biology, innate immunity, bioforensics and security analysis. These research efforts can be applied to biothreat reduction and biodefense, protection of nuclear worker health and safety, advances in pharmaceuticals and general public health measures. What's New?New Algorithm for the Computational Validation of Nucleic Acid-based Detection AssaysJason Gans and Murray Wolinsky (B-7) recently published an article in Nucleic Acids Research titled “Improved assay-dependent searching of nucleic acid sequence databases” (Nucleic Acids Research Advance Access published online on May 31, 2008). This paper describes a new algorithm for the computational validation of nucleic acid-based detection assays. Read More... First Research on Host Immunity in Airway Epithelial Cells to Beryllium ExposureElizabeth Hong-Geller (B-7) and co-authors Shannan Rodriguez (B-9), Yuliya Kunde (B7), and T. Mark McCleskey (MPA-MC) have published an article "Upregulation of I-CAM1 in response to beryllium exposure in small airway epithelial cells" in the journal Toxicology Letters. Chronic Beryllium Disease (CBD) is a delayed-type hypersensitivity immune reaction that leads to granuloma formation in the lungs and potentially severe loss of pulmonary function. Read More... |
B-7 Teams
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