Pathogen detection made easy with Biological Identification and Quantification (BIOIQ)
BIOIQ employs LANL proprietary dyes for detection of the presence of microorganisms of a specific species or strain. LANL has demonstrated this technology with Bg spores and vegetative E. coli.
Contact
- David Hadley
- (505) 667-7539
Biological identifier and quantifier for pathogens
Applications
- Pathogen detection and identification
Benefits
- BIOIQ is a large advancement over current technologies that use PCR, or immunoassays
- BIOIQ uses a simple system of direct detection on sample media, eliminating or reducing time, energy, size constraints, and consumables
Efficient field or point of care diagnostics rely on speed, low cost, ease of use, and ability to quantitate allowing for proper selection of methods and timely, effective equipment and personnel release or patient treatment. Inexpensive, hand-held technologies that can quantitate a pathogen are basically nonexistent in the field today. Needs for pathogen detection and identification can be realized with a novel patent-pending LANL technology Biological Identification and Quantification or BIOIQ, which identifies and quantifies any strain or species of microorganism in real-time.
BIOIQ employs LANL proprietary dyes for detection of the presence of microorganisms of a specific species or strain. LANL has demonstrated this technology with Bg spores and vegetative E. coli. The detection of multiple pathogens is accomplished by using a dye set, which allows for a screening or general detection of human pathogens of interested. Multiple species can be identified simultaneously.
LANL’s patent pending technology and custom dyes can detect a specific microorganism or a tailored set by nucleic acid sequence. The device will accept a sample collected from air, blood, urine, serum, water, or a surface, the sample inserted into a reader, result obtained in minutes, data stored internally and transmit to an offsite location. No sample preparation or extraction is needed decreasing current detection limits and failures. The unaltered sample can be used for further subse- quent analysis.
The future detection platform would use commercially available components and supplies for ease of manufacture/deployment. The platform will be battery operated, rugged, and field deployable. Success is very likely to result in a hand-held possibly palm-sized device for field or point-of-care pathogen detection.
Development Stage: LANL and the Lviv Institute of Epidemiology, Ukraine, are at the initial stages of proposal development.
Patent Status: Patent pending.
Licensing Status: Available for licensing once project is developed.
Related Articles
All Stories
Bees replacing dogs as detectors of volatile organic compounds
August, 6 2012 - Researchers at LANL began working with domestic honeybees in 2006 to detect explosive materials and narcotics.
Increased durability and lifetime of fuel cell products
April, 3 2012 - A revolutionary method of building a membrane electrode assembly (MEA) for PEM fuel cells allows LANL to offer significant cost reductions and performance enhancements necessary for mainstream applications.
Digital content tool analyzes "gist" of text-based documents
April, 3 2012 - LANL’s Digital Knowledge Discovery Team has created a suite of digital-content-analysis tools to gather, reduce, annotate, organize, synthesize, and visualize digital content.
Reinvention of laboratory apparatus cuts costs
April, 3 2012 - New apparatus that is designed to be inexpensive, reconfigurable, and adaptable to both surface and solution electrochemical experiments.
Solving the energy overusage problem
April, 3 2012 - Energy use and related thermal management issues are serious business concerns, but with EnergyFit LANL can significantly reduce heat output and maintain consistent electrical cost.
Hazardous odorless gases detected by LANL's IntelliCLAD
April, 3 2012 - This new class of smart coatings are non-odorous but release an odor in the presence of selected gases of concern, reducing contamination and alerting people when danger arises.
Programers advance with Kip Ray Tracer
April, 3 2012 - Kip is a high-performance ray tracing library that provides rapid rendering and compact code while using very little memory so large numbers of shapes can be used simultaneously.
KIVA's modeling code increases engine efficiency and fuel economy
April, 3 2012 - Through an advanced computational modeling code that accurately simulates the in-cylinder processes of engines, LANL scientists have addressed many costly issues.
Deep-space communication improved with electromagnetic radiation antenna
April, 3 2012 - New antenna has potential applications in RADAR, secure communications, ultra-long-range communications, oncology and astrophysics.
Faster than the speed of sight: High-speed camera provides high sensitivity, frame rate
April, 3 2012 - High-speed cameras becomes less effective at high speeds; MOXIE fixes that problem by simultaneously providing both the highest photographic and physical speeds.
Video
Small Reactor for Deep Space Exploration
This is the first demonstration of a space nuclear reactor system to produce electricity in the United States since 1965, and an experiment demonstrate...
